Bactrim is a combination of two antibiotics: trimethoprim and sulfamethoxazole. Generic Bactrim is used to treat: ear infections, urinary tract infections, bronchitis, traveler’s diarrhea, Pneumocystis carinii pneumonia. Generic Bactrim fights against bacteria in your body.
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What is Bactrim?
Sulfamethoxazole and trimethoprim combination is used to treat infections such as urinary tract infections, middle ear infections (otitis media), bronchitis, traveler’s diarrhea, and shigellosis (bacillary dysentery). This medicine is also used to prevent or treat Pneumocystis jiroveci pneumonia or Pneumocystis carinii pneumonia (PCP), a very serious kind of pneumonia. This type of pneumonia occurs more commonly in patients whose immune systems are not working normally, such as cancer patients, transplant patients, and patients with acquired immune deficiency syndrome (AIDS).
Sulfamethoxazole and trimethoprim combination is an antibiotic. It works by eliminating the bacteria that cause many kinds of infections. This medicine will not work for colds, flu, or other virus infections.
This medicine is available only with your doctor’s prescription.
Generic names of Generic Bactrim are Sulfamethoxazole, Trimethoprim. Brand names of Generic Bactrim are Bactrim.
Bactrim Dosage for UTI
The usual adult dosage in the treatment of urinary tract infections is 2 Bactrim tablets every 12 hours for 10 to 14 days. An identical daily dosage is used for 5 days in the treatment of shigellosis.
Traveler’s Diarrhea in Adults
For the treatment of traveler’s diarrhea, the usual adult dosage is 2 Bactrim tablets every 12 hours for 5 days.
The recommended dosage for treatment of patients with documented Pneumocystis jiroveci pneumonia is 75 to 100 mg/kg sulfamethoxazole and 15 to 20 mg/kg trimethoprim per 24 hours given in equally divided doses every 6 hours for 14 to 21 days.
Bactrim for Bronchitis Dosage
The usual adult dosage in the treatment of acute exacerbations of chronic bronchitis is 2 BACTRIM tablets every 12 hours for 14 days.
If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. Do not double the dose to catch up.
Often, there is no need for treatment for an overdose of antibiotics. Usually, you should look at abdominal pain and possibly diarrhea. In this case, you must provide additional liquids.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medicines out of the reach of children and pets.
Do not rinse the medication in the laundry room or drain it unless instructed to do so. Discard this product when it has expired or is no longer needed. Contact your pharmacist or your local waste disposal company.
Possible Side Effects
The most common side effect of Bactrim is nausea. Call your doctor if it worsens or does not go away, or if you experience:
- stomach ache,
- anorexia, or loss of appetite.
Some other common side effects might be an early sign of a more severe reaction, so if you experience the following, stop taking the drug and call your doctor right away:
Tell your doctor right away or get emergency medical help if you experience:
- sore throat and cough,
- severe, prolonged diarrhea that may occur with fever and stomach cramps, which possibly indicates a C. difficile infection,
- fever or chills,
- trouble breathing,
- unusual bruising or bleeding,
- yellowing of the skin and eyes (jaundice),
- joint or muscle pain,
- spots on the skin that are purple or reddish (purpura),
Bactrim is contraindicated in patients with a known hypersensitivity to trimethoprim or sulfonamides, in patients with a history of drug-induced immune thrombocytopenia with use of trimethoprim and/or sulfonamides, and in patients with documented megaloblastic anemia due to folate deficiency.
Bactrim is contraindicated in pediatric patients less than 2 months of age. Bactrim is also contraindicated in patients with marked hepatic damage or with severe renal insufficiency when renal function status cannot be monitored.
Pregnancy and Bactrim
Before taking Bactrim, tell your doctor if you are pregnant or may become pregnant.
It should only be used during pregnancy if the benefits clearly outweigh the potential harms to the unborn child.
You should not breastfeed when taking Bactrim. The drug is excreted in breast milk and has the potential to harm breastfeeding infants, especially if they are ill, stressed, or premature.
What are the Effects of Drinking Alcohol while Taking Bactrim?
Antibiotics and alcohol can cause similar side effects, such as stomach pain, dizziness and drowsiness. The combination of antibiotics and alcohol can increase these side effects.
Bactrim should not be mixed with alcohol because it can lead to a more serious reaction. Drinking any amount of alcohol with this medicine can lead to side effects such as redness, headache, nausea and vomiting, and rapid heart rate.
Is Bactrim a strong antibotic?
By range of organisms targeted, however, trimethoprim and sulfamethoxazole can be considered very powerful: despite not being a bactericide like penicillin, it can treat conditions ranging from traveler’s diarrhea to urinary tract infections to resistant staphylococcal infections (MRSA) to the now-rarely-seen Pneumocystis jiroveci pneumonia of AIDS.
How do sulfamethoxazole and trimethoprim work?
Sulfamethoxazole is a sulfonamide antibiotic that limits the growth of bacteria. Sulfonamides inhibit synthesis of folic acid, important to bacterial DNA synthesis. Trimethoprim works by starving the bacteria of nucleotides necessary for DNA replication.
Bactrim Other Names
- Bactrim, Cosig, Resprim, Septrin, Trimoxazole (Australia)
- Apo-Sulfatrim, Novo-Trimel, Nu-Cotrimox, Septra (Canada)
- Fectrim, Septrin (UK)
- Bactrim, Cotrim, Septra, SMZ-TMP, Sulfatrim (USA)